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DeCS
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Descriptor English:
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Tissue Distribution
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Descriptor Spanish:
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Distribución Tisular
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Descriptor Portuguese:
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Distribuição Tecidual
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Synonyms English:
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Distribution, Tissue
Distributions, Tissue
Tissue Distributions
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Tree Number:
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G03.787.917
G07.690.725.949
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Definition English:
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Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios. |
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Indexing Annotation English:
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distrib of drugs or chem in organs & tissues; GEN only: not a substitute for organ /metab or organ /chem; never IM; coord NIM with substance /pharmacokin (IM) or /metab (IM)
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History Note English:
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78
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Allowable Qualifiers English:
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Record Number:
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23482
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Unique Identifier:
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D014018
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Occurrence in VHL:
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Similar:
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DeCS
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